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2009


Kondo N., Nishimura S.-I., (2009) MALDI-TOF mass spectrometry-based versatile method for the characterization of protein kinases. Chem. Eur. J. 15, 1413-1421.
Manabe O, Yoshinaga K, Katoh C, Naya M, DeKemp RA, Tamaki N, (2009) Repeatability of rest and hyperemic myocardial blood flow measurements with Rb-82 dynamic PET. J Nucl Med. 50:68-71.
Wu C, Irie S, Yamamoto S, et al. (2009) A bioluminescent enzyme immunoassay for prostaglandin E2 using Cypridina luciferase. Luminescence. 24: 131-133.
Shiga T, Morimoto Y, Kubo N, et al. (2009) A new PET with semiconductor detectors enables better identification of intratumoral inhomogeneity. J Nucl Med. 50, 148-155.
Ueno Y, Morimoto Y, Tsuchiya K, et al. (2009) Basic performance test of a prototype PET scanner using CdTe semiconductor detectors, IEEE Trans. Nucl. Sci. 56, 24-28.
Sokabe M, Ose T, Nakamura A, Tokunaga K, Nureki O, Yao M, Tanaka I, (2009) The structure of alanyl-tRNA synthetase with editing domain. Proc. Natl. Acad. Sci. 106, 11028-11033.
Chimnaronk S, Suzuki T, Manita T, Ikeuchi Y, Yao M, Suzuki T, Tanaka I, (2009) RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon. The EMBO J. 28, 1362-1373.
Tanaka Y, Yamagata S, Kitago Y, Yamada Y, Chimnaronk S, Yao M, Tanaka I, (2009) Deduced RNA binding mechanism of ThiI based on structural and binding analyses of a minimal RNA ligand. RNA, 15, 1498-1506.
Okuyama M, Kitamura M, Hondoh H, Kang M-S, Mori H, Kimura A, Tanaka I, Yao M, (2009) Catalytic Mechanism of Retaining α-Galactosidase Belonging to Glycoside Hydrolase Family 97. J. Mol. Biol. 392, 1232-1241.
Chimnaronk S, Forouhar F, Sakai J, Yao M, Tron C-M, Atta M, Fontecave M, Hunt J-F, Tanaka I, (2009) Snapshots of Dynamics in Synthesizing N6-Isopentenyladenosine at the tRNA Anticodon. Biochemistry, 48, 5057-5065.
Watanabe N, Takasaki Y, Sato C, Ando S, Tanaka I, (2009) Structures of restriction endonuclease HindIII in complex with its cognate DNA and divalent cations. Acta Cryst. D65, 1326-1333.
Hinou H, Saito N, Ogawa M, Maeda T and Nishimura S.-I., (2009) Microwave Effect for Glycosylation Promoted by Solid Super Acid in Supercritical Carbon Dioxide. Int. J. Mol. Sci., 10, 5285-5295.
Hinou H and Nishimura S.-I, (2009) Mechanism-Based Probing, Characterization, and Inhibitor Design of Glycosidases and Glycosyltransferases. Curr. Top. Med. Chem., 9, 106-116.
Nagahori N, Abe M, Nishimura S.-I, (2009) Structural and functional glycosphingolipidomics by glycoblotting with aminooxy-functionalized gold nanoparticle. Biochemistry, 48, 583-594.
Matsushita T, Sadamoto R, Ohyabu N, Nakata H, Fumoto M, Fujitani N, Takegawa Y, Sakamoto T, Kurogochi M, Hinou H, Shimizu H, Ito T, Naruchi K, Togame H, Takemoto H, Kondo H, Nishimura S.-I., (2009) Functional Neoglycopeptides: Synthesis and Characterization of New Class MUC1 Glycoprotein Models Having Core 2-based O-Glycan and Complex-type N-Glycan Chains. Biochemistry, 48, 11117-11133.
Ohyabu N, Hinou H, Matsushita T, Izumi R, Shimizu H, Kawamoto K, Numata Y, Togame H, Takemoto H, Kondo H, Nishimura S.-I., (2009) An Essential Epitope of Anti-MUC1 Monoclonal Antibody KL-6 Revealed by Focused Glycopeptide Library. J. Am. Chem. Soc., 131, 17102-17109.
Ueda T, Tomita K, Notsu Y, Ito T, Fumoto M, Takakura T, Nagatome H, Takimoto A, Mihara S-I., Togame H, Kawamoto K, Iwasaki T, Asakura K, Oshima T, Hanasaki K, Nishimura S-I., Kondo H, (2009) Chemoenzymatic Synthesis of Glycosylated Glucagon-like Peptide 1: Effect of Glycosylation on Proteolytic Resistance and in vivo Blood Glucose- lowering Activity. J. Am. Chem. Soc., 131, 6237-6245.
Uematsu R, Shinohara Y, Nakagawa H, Kurogochi M, Furukawa J.-i, Miura Y, Akiyama M, Shimizu H, Nishimura S.-I., (2009) Glycosylation specific for adhesion molecules in epidermis and its receptor revealed by glycoform-focused reverse genomics. Mol. Cell. Proteom., 8, 232-244.
Honma K, Honma S, (2009) The SCN-independent clocks, methamphetamine and food restriction. Eur.J.Neurosci., 30:1707-1717.
Yasuda K, Kitamura N, Gong JP, Arakaki K, Kwon HJ, Onodera S, Chen YM, Kurokawa T, Kanaya F, Ohmiya Y, Osada Y, (2009) A Novel Double-Network Hydrogel Induces Spontaneous Articular Cartilage Regeneration In Vivo in a Large Osteochondral Defec. Macromol. Biosci., 9, 307-316.
Akimoto H, Kwon HJ, Ozaki M, Yasuda K, Honma K, Ohmiya Y, (2009) In vivo bioluminescence imaging of bone marrow-derived cells in brain inflammation. Biochem. Biophys. Res. Commun., 380, 844-849.
Misu M, Furukawa H, Kwon HJ, Shikinaka K, Kakugo A, Sato T, Osada Y, Gong JP, (2009) Photoinduced in situ Formation of Various F-Actin Assemblies with Photoresponsive Polycation. Journal of Biomedical Materials Research: Part A., 89, 424-431.
Tohyama H, Yasuda K, Minami A, Majima T, Iwasaki N, Muneta T, Sekiya I, Yagishita K, Takahashi S, Kurokouchi K, Uchio Y, Iwasa J, Deie M, Adachi N, Sugawara K, Ochi M, (2009) Atelocollagen-associated autologous chondrocyte implantation for the repair of chondral defects of the knee: a prospective multicenter clinical trial in Japan. J Orthop Sci., 14, 579-88.
Chiba Y, Kuroda S, Maruichi K, Osanai T, Hokari M, Yano S, Shichinohe H, Hida K, Iwasaki Y, (2009) Transplanted bone marrow stromal cells promote axonal regeneration and improve motor function in rat spinal cord injury model. Neurosurgery 64:991-1000.
Maruichi K, Kuroda S, Chiba Y, Hokari M, Shichinohe H, Hida K, Iwasaki Y, (2009) Transplanted bone marrow stromal cells improves cognitive dysfunction due to diffuse axonal injury in rats. Neuropathology 29:422-432.
Itosaka H, Kuroda S, Shichinohe H, Yasuda H, Yano S, Kamei S, Kawamura R, Hida K, Iwasaki Y, (2009) Fibrin matrix provides a suitable scaffold for bone marrow stromal cells transplanted into injured spinal cord - A novel material for CNS tissue engineering. Neuropathology 29:248-257.
Hokari M, Kuroda S, Chiba Y, Maruichi K, Iwasaki Y, (2009) Synergistic effects of granulocyte-colony stimulating factor on bone marrow stromal cell transplantation for mice cerebral infarct. Cytokine 46:260-266.
Maruichi K, Kuroda S, Chiba Y, Hokari M, Shichinohe H, Hida K, Iwasaki Y, (2009) Graded model of diffuse axonal injury for studying head injury-induced cognitive dysfunction in rats. Neuropathology 29:132-139.
Naya M, Tsukamoto T, Morita K, Katoh C, Nishijima K, Komatsu H, Yamada S, Kuge Y, Tamaki N, Tsutsui H, (2009) Myocardial beta-adrenergic receptor density assessed by 11C-CGP12177 PET predicts improvement of cardiac function after carvedilol treatment in patients with idiopathic dilated cardiomyopathy. J Nucl Med 50: 220-225.
Kuge Y, Obokata N, Kimura H, Katada Y, Temma T, Sugimoto Y, Aita K, Seki K, Tamaki N, Saji H, (2009) Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression. Nucl Med Biol 36:869-876.
Kuge Y, Zhao S, Takei T, Tamaki N, (2009) Molecular imaging of apoptosis with radio-labeled Annexin A5 focused on the evaluation of tumor response to chemotherapy. Anticancer Agents Med Chem 9:1003-1011.
Shichinohe H, Kuroda S, (2009) Bone marrow stromal cell transplantation for cerebral infarction - recent advances and perspective. Res Adv in Stroke 1:23-35.
Kuge Y, (2009) Chapter 11 Technetium-99m Annexin-A5 for Apoptosis Imaging. In: Technetium-99m Radiopharmaceuticals: Status and Trends. IAEA RADIOISOTOPES AND RADIOPHARMACEUTICALS SERIES No. 1. INTERNATIONAL ATOMIC ENERGY AGENCY, VIENNA, pp.241-253.
Inoue T, Shimizu S, Onimaru R, Takeda A, Onishi H, Nagata Y, Kimura T, Karasawa K, Arimoto T, Hareyama M, Kikuchi E, Shirato H, (2009) Clinical outcomes of stereotactic body radiotherapy for small lung lesions clinically diagnosed as primary lung cancer on radiologic examination. Int J Radiat Oncol Biol Phys. Nov 1;75(3):683-7.
Borst GR, Ishikawa M, Nijkamp J, Hauptmann M, Shirato H, Onimaru R, van den Heuvel MM, Belderbos J, Lebesque JV, Sonke JJ, (2009) Radiation pneumonitis in patients treated for malignant pulmonary lesions with hypofractionated radiation therapy. Radiother Oncol. Jun;91(3):307-13.
Nishioka K, Abo D, Aoyama H, Furuta Y, Onimaru R, Onodera S, Sawamura Y, Ishikawa M, Fukuda S, Shirato H, (2009) Stereotactic Radiotherapy for Intracranial Nonacoustic Schwannomas Including Facial Nerve Schwannoma. Int J Radiat Oncol Biol Phys. Dec 1;75(5):1415-9.
Suzuki K, Nishioka T, Homma A, Tsuchiya K, Yasuda M, Aoyama H, Onimaru R, Tamaki N, Shirato H, (2009) Value of fluorodeoxyglucose positron emission tomography before radiotherapy for head and neck cancer: does the standardized uptake value predict treatment outcome?, Jpn J. Radiol. Jul;27(6):237-42.
Nagata Y, Hiraoka M, Mizowaki T, Narita Y, Matsuo Y, Norihisa Y, Onishi H, Shirato H, (2009) Survey of stereotactic body radiation therapy in Japan by the Japan 3-D Conformal External Beam Radiotherapy Group. Int J Radiat Oncol Biol Phys. Oct 1;75(2):343-7.
Shimizu S, Hosokawa M, Itoh K, Fujita M, Takahashi H, Shirato H, (2009) Can hybrid FDG-PET/CT detect subclinical lymph node metastasis of esophageal cancer appropriately and contribute to radiation treatment planning? A comparison of image-based and pathological findings. Int J Clin Oncol. Oct;14(5):421-5.
Suzuki K, Hirasawa Y, Yaegashi Y, Miyamoto H, Shirato H. A web-based remote radiation treatment planning system using the remote desktop function of a computer operating system: a preliminary report. J Telemed Telecare.
Park HC, Shimizu S, Yonesaka A, Tsuchiya K, Ebina Y, Taguchi H, Katoh N, Kinoshita R, Ishikawa M, Sakuragi N, Shirato H, High dose three-dimensional conformal boost using the real-time tumor tracking radiotherapy system in cervical cancer patients unable to receive intracavitary brachytherapy. Yonsei Med J. Epub.
Tha KK, Terae S, Kudo K, Miyasaka K, (2009) Differential diagnosis of hyperintense cerebrospinal fluid on fluid-attenuated inversion recovery images of the brain. Part II: non-pathological conditions. Br J Radiol. Jul;82(979):610-4. Review.
Tha KK, Terae S, Kudo K, Miyasaka K, (2009) Differential diagnosis of hyperintense cerebrospinal fluid on fluid-attenuated inversion recovery images of the brain. Part I: pathological conditions. Br J Radiol. May;82(977):426-34. Review.
Chamoto K, Takeshima T, Wakita D, Ohkuri T, Ashino S, Omatsu T, Shirato H, Kitamura H, Togashi Y, Nishimura T, (2009) Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells. Cancer Sci. May;100(5):934-9.
Ishikawa M, Bengua G, Sutherland K, Hiratsuka J, Katoh N, Shimizu S, Aoyama H, Fujita K, Yamazaki R, Horita K, Shirato H, (2009) A feasibility study of novel plastic scintillation dosimetry with pulse counting mode. Phys Med Biol. 54:2079-2092.
Hatakeyama H, Ito E, Akita H, Oishi M, Nagasaki Y, Futaki S, Harashima H, (2009) A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo. J. Control. Release, 139, 127-132.
Sakurai Y, Hatakeyama H, Akita H, Oishi M, Nagasaki Y, Futaki S, Harashima H, (2009) Efficient siRNA delivery to tumor cells using the combination of octaarginine, GALA and tumor-specific, cleavable PEG system. Biol. Pharm. Bull. 32, 928-932.
Kawai-Noma S, Pack CG, Tsuji T, Kinjo M, Taguchi H, (2009) Single mother-daughter pair analysis to clarify the diffusion properties of yeast prion Sup35 in guanidine-HCI-treated [PSI] cells. Genes Cells, 14(9), 1045-54.
Ito T, Oshita S, Nakabayashi T, Sun F, Kinjo M, Ohta N, (2009) Fluorescence lifetime images of green fluorescent protein in HeLa cells during TNF-alpha induced apoptosis. Photochem Photobiol Sci., 8(6), 763-7.106.

Coordinating Office, Future Drug Discovery and Medical Care Innovation Project
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