Center for Promotion of Platform for Research on Biofunctional Molecules
On the Management of Platform for
Research on Biofunctional Molecules (PRBM)
Director, Center for Promotion of PRBM, Hokkaido University
Toshiaki KODA, M.D., Ph.D.
The Platform for Research on Biofunctional Molecules (PRBM) of Hokkaido University, situated on its North Campus, represents a newly built research facility dedicated to rearing experimental animals, such as mouse, and conducting various medical experiments on them. The Center for Promotion of PRBM oversees the overall management of these research activities. Experiments on disease-carrying animals are conducted to investigate the curing effect as well as the side-effects of newly developed drugs especially during the drug discovery stage. Besides, the Platform will promote research aimed at elucidating the diversity of the intestinal/bowel functions at nanometric scale in conjunction with the development of novel biofunctional materials.
In addition, PRBM is equipped with the state of the art equipment for microscopic observations: (i) a high-resolution (3 nm) Spin-Polarized Scanning Electron Microscope (Spin SEM) for analyzing spin distribution, elements distribution, and crystalline structure of samples in connection with advanced technological innovation in various areas; and (ii) a digital electron diffraction microscope with de Broglie wavelength functionality that allows non-destructive diffractive imaging of target specimens (DNA, carbon nano-tubes) and hence precise structural observations at atomic scale. The Center plans to make these cutting-edge research facilities widely available for collaborative research.
We put emphasis on using the resources available at PRBM to materialize vigorous collaborative research with businesses/industries, namely, Shionogi & Co. Ltd. including Shionogi Innovation Center for Drug Discovery, Nitto Denko Corporation, Primary Cell Co. Ltd. Also, we will cooperate with the neighboring regional R&D institutions and incubation facilities, such as Hokudai Business Spring. Parallel to these activities, we expect to set up Open Laboratories to further expand the sphere of research activities through projects led and participated by researchers both from inside and outside Hokkaido University.